Elucidation of mixed surfactants reducing mass transfer resistance during high-solids enzymatic hydrolysis from lignocellulosic biomass
文献类型： 外文期刊
作者： Liu, Qiangqiang 1 ; Sun, Chihe 1 ; Madadi, Meysam 1 ; Zhang, Ezhen 2 ; Xia, Ao 3 ; Samimi, Abdolreza 4 ; Sun, Fubao 1 ;
作者机构： 1.Jiangnan Univ, Sch Biotechnol, Key Lab Ind Biotechnol, Minist Educ, Wuxi 214122, Peoples R China
2.Guangxi Acad Agr Sci, Inst Agroprod Proc Sci & Technol, Nanning 530007, Peoples R China
3.Chongqing Univ, Key Lab Low grade Energy Utilizat Technol & Syst, Minist Educ, Chongqing 400044, Peoples R China
4.Univ Sistan & Baluchestan, Dept Chem Engn, Zahedan, Iran
关键词： Lignocellulosic Biomass; Enzymatic Hydrolysis; Mass Transfer Characteristics; Surfactant Synergy; Diffusion
期刊名称：CHEMICAL ENGINEERING JOURNAL （ 影响因子：13.2； 五年影响因子：13.5 ）
ISSN： 1385-8947
年卷期： 2025 年 507 卷
页码：
收录情况： SCI
摘要： The production of fermentable sugars from lignocellulosic biomass (LCB) via high-solids enzymatic hydrolysis (EH) is crucial for sustainable enzyme-based biorefineries. However, multi-scale mass transfer resistance limits EH efficiency, particularly under conditions of low cellulase dosages and high substrate loadings. This study revealed the substantial benefits of a synergistic surfactant formulation in enhancing the transfer behavior of cellulases and sugar products. From a macroscopic scale, ternary surfactants (Tween 60, Triton X-114, and CTAB) markedly reduced the slurry viscosity by 48 %similar to 65 % compared to control groups, promoting efficient convective diffusion of cellulases to particle surfaces during the early EH stage. At the subsequent pore-scale rate-limiting process, mixed surfactants helped cellulases stay in their monomeric form (< 8.9 nm), reducing steric hindrance in internal micropores. Also, the uniform substrate dispersion with fewer secondary pores among aggregated particles resulted in 56 % and 115 % increases in transfer resistance constants and protein adsorption rates, respectively. Essentially, the increased water activity (with 80 % more free water) and reduced particle interactions (solid-liquid interfacial tension reduced by up to 78 %) were the key drivers in improving mass transfer in the presence of mixed surfactants. Overall, surfactant synergism achieved a total sugar titer of 146 g/L during 20 % batch EH, leading to similar to 80 % of both 72-h glucose and xylose yields. This study provides valuable insights into the multi-scale mass transfer enhancement achieved through synergistic surfactant action in highsolids EH.
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